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"I was having some trouble on a fresh conda environment for bigscape and noticed a break when calculating the networks (post-hmmer). Following along with the install page, I was using the latest scikit-learn (0.20.2) and the break has something to do with that. I'm not exactly sure what the issue is, but it's resolved by forcing scikit-learn version 0.19.1 in the environment setup."

Reported by Marc C